Read e-book online Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms, PDF

By Linda A. Felton, James W. McGinity

ISBN-10: 0849387892

ISBN-13: 9780849387890

This hugely praised ebook provides an in-depth research of actual and chemical houses and functions of aqueous-based polymeric coatings-covering covered dosage types, movie defects, and polymer characterization. New chapters on plastisizers and their purposes in pharmaceutical coatings, adhesion of polymeric motion pictures to good substrates, and the impression of pigments on houses of the polymeric coating structures are integrated during this 3rd version. also, this identify presents new fabric on polymer interactions with medicines and excipients and actual getting older of polymeric motion pictures.

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Additional resources for Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms, 3rd Edition (Drugs and the Pharmaceutical Sciences)

Example text

Using small-angle neutron scattering (SANS), Chevalier et al. (5) demonstrated a reversible compression of the latex-in-water dispersion to a latex-inwater foam, followed by irreversible coalescence of the foam with inversion to a water-in-latex topology. Water is involved in both stages. Coalescence depends on the fragmentation of the foam membranes. The phase inversion involves connection of latex domains and fragmentation of water domains, driven by the spontaneous curvature of membranes according to their water content.

Steward provides a very comprehensive online review and discussion of the relevant detailed theory on his Web site (11). Sperry et al. (12) used predried controls to investigate the role of water in film formation using the transition from an opaque to a clear film [the minimum film-forming temperature (MFFT)]. Latices predried at temperatures below their MFFT were compared to wet latices. Using hydrophobic polymers, the dry MFFT was virtually identical to the wet MFFT, indicating that capillary forces contributed little to film formation.

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Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms, 3rd Edition (Drugs and the Pharmaceutical Sciences) by Linda A. Felton, James W. McGinity


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