By Professor Dr. Endre Kelemen, Professor Dr. Wenceslao Calvo, Professor Dr. Theodor M. Fliedner (auth.)
During the prior two decades, celJ biology has made large strides that have thoroughly remodeled the widely used morphological hematology of the day before today. This growth is essentially as a result of the advent of recent options which permit practical instead of anatomic reviews: labeling thoughts have made attainable the learn of celJ kinetics from beginning to dying of a celJ: tradition options (both in vivo and in vitro) have made it attainable to set up the progeny of definite stern celJs, their development poten tiaL and the mechanisms in their legislation. the consequences were so notable and feature so aroused the keenness 01' younger hematologists that it has develop into stylish in so me quarters to think about the microscope an "extinct device" and morphology littlc greater than an superseded (if agreeable) hobby of little clinical curiosity. one of many results is the want of a few investigators to review cytology with no the help of their eyes. the current ebook makes us become aware of once again that morphology is the technology of constitution and form and that its objective isn't really to colJect images yet to appreciate them. it's actual that microscopic commentary, even if made with the electron microscope, can't on its own resolution a few simple questions of celJ biology. despite the fact that, the hematologist who makes use of just a unmarried process is sort of a one that may describe the area from the viewpoint of a unmarried sensory organ and could refuse assistance from the others.
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Additional resources for Atlas of Human Hemopoietic Development
The two inner layers show yolk sac endoderm and the two outer layers (upper and /oll'er margins of the picture) show the outer mesothelial surface. Between the two layers one can see loose mesenchym al tissue, with relatively large vessels, containing primitive erythroblasts (/oll'er part) and several denuc1eated red cells (upper part). In the /OIl'er part, several primitive erythroplasts appear to be located extravascularly in the endodermal area. Apparently free hemopoietic cells can also be seen in the endcderm at the upper part.
12 Intraembryonie, Extraorganic Hemopoiesis Megakaryocytes can be found. single or forming sm all clusters, m the connective tissue of the abdominal and thoracic cavities. a Group of seven megakaryocytes in various stages of development found in the connective tissue around the solar plexus of an 8-week-old embryo. Methacrylate. Giemsa, x 500. band c Megakaryocytes found in the paravertebral conective tissue and in the neck of the same embryo. Methacrylate. Giemsa, x 500 EMBRYONIC AND FETAL HEMOPOIESIS a 47 2 Intravascular Hemopoietic Cells Chapter 2 examines the types of ce11s that can be detected in the circulating blood during embryonie and fetal development.
At early stages of li ver hemopoiesis, one may identify hemocytob1ast-like cells located extravascularly in the endoderm. f. THOMAS and YOFFEY 1964, HOYES et al. 1973, FUKUDA 1974). Embryonic, but Extraorganic Hemopoiesis. In the 100se connective tissue of the 10w cervica1 region, in the thorax, abdomen, and even sometimes in the extremities, small groups of extravascular hemopoietic cells are easy to find, mostly in the form of co10nies of on1y one cell type. 10. 11) and megakaryopoietic clusters in the cervical region and in the abdominal cavity can be seen.
Atlas of Human Hemopoietic Development by Professor Dr. Endre Kelemen, Professor Dr. Wenceslao Calvo, Professor Dr. Theodor M. Fliedner (auth.)